PRR23C

Across TCGA patient cohorts, PRR23C mutation is significantly associated with the RNA expression of many other genes, with 1,712 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR23C-associated genes across cancer lineages are MIR6781, ZNF600, and SH2D5. Each is linked with PRR23C in more than 2 cancer types. Because this analysis shows association rather than direction, both PRR23C-to-partner and partner-to-PRR23C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6781 grouped by PRR23C-low versus PRR23C-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR23C→partner) and Y-score (partner→PRR23C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR6781 →	+0.752	+4.307	.001	<.001	3	3
UCEC	ZNF600 →	+0.389	+2.863	.003	.001	3	2
UCEC	SH2D5 →	+0.589	+2.732	<.001	.003	3	2
UCEC	MIER1 →	+0.548	+2.247	.002	.002	3	2
UCEC	C4orf46 →	+0.562	+3.201	.001	.009	3	2
UCEC	CNEP1R1 →	+0.469	+2.839	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,712 associations by consensus.

MIR6781 by PRR23C expression — COAD

Explore this box plot interactively →