PRR23C

Across TCGA cell cohorts, PRR23C mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible PRR23C-associated genes across cancer lineages are FEV, OR52I1, and PRAMEF33. Each is linked with PRR23C in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR23C-to-partner and partner-to-PRR23C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FEV grouped by PRR23C-low versus PRR23C-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR23C→partner) and Y-score (partner→PRR23C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	FEV →	+0.072	+2.560	<.001	.009	3	1
SKIN	OR52I1 →	+0.014	+3.502	.006	.007	3	1
SKIN	PRAMEF33 →	+0.008	+3.415	<.001	.001	3	1
SKIN	PRAMEF11 →	+0.020	+2.669	.002	.004	3	1
BLOOD_Leukemia	GUCA1C →	+0.023	+4.384	<.001	.006	3	1
BLOOD_Leukemia	TEX43 →	+0.084	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

FEV by PRR23C expression — SKIN

Explore this box plot interactively →