Across TCGA cell cohorts, PRR23A mutation is significantly associated with the RNA expression of many other genes, with 80 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PRR23A-associated genes across cancer lineages are CASP14, FAM149A, and ELOVL3. Each is linked with PRR23A in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR23A-to-partner and partner-to-PRR23A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR23A→partner) and Y-score (partner→PRR23A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CASP14 →	+0.061	+3.011	.008	.008	3	1
LARGE_INTESTINE	FAM149A →	+1.281	+3.364	.001	.002	3	1
LARGE_INTESTINE	ELOVL3 →	+1.016	+3.064	<.001	.009	3	1
LARGE_INTESTINE	RPAP2 →	+0.552	+3.364	.007	.002	3	1
LARGE_INTESTINE	PRKCG →	+0.801	+3.364	.005	.002	3	1
LARGE_INTESTINE	GASK1A →	+0.758	+3.308	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 80 associations by consensus.

Exploration

PRR23A survival (RNA) · tumor vs normal (RNA) · all PRR23A data types