PRR15L

Across TCGA pan-cancer cohorts, PRR15L mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PRR15L data layer compared with 24 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PRR15L mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PRR15L expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and UCEC are the cancer types where PRR15L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.917	.022	48	view →
PDAC	DFS	Tertile	All	0.551	0.332	.005	40	view →
UCEC	DFS	Tertile	All	0.986	0.801	.007	16	view →
CCRCC	DFS	Tertile	III,IV	0.141	0.777	.027	8	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.932	.034	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PRR15L–COAD (DFS)

Open the COAD breakdown →