Across TCGA pan-cancer cohorts, PRR14L mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated PRR14L data layer compared with 28 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PRR14L mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PRR14L expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

UCEC, LUAD, and CCRCC are the cancer types where PRR14L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	1.000	0.386	.002	32	view →
LUAD	OS	Quartile	II,III,IV	0.868	0.331	.010	8	view →
CCRCC	DFS	Quartile	All	0.384	1.000	.038	2	view →
HNSC	OS	Tertile	All	0.982	0.702	.017	2	view →
GBM	OS	Median	All	0.452	0.303	.046	1	view →
LSCC	OS	Median	All	1.000	0.793	.025	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: PRR14L tumor-vs-normal RNA expression · all PRR14L data types