Across TCGA patient cohorts, PRR14L protein abundance is significantly associated with the RNA expression of many other genes, with 8,731 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRR14L-associated genes across cancer lineages are CCNB1, UFD1, and KIF20A. Each is linked with PRR14L in more than 4 cancer types. Because this analysis shows association rather than direction, both PRR14L-to-partner and partner-to-PRR14L results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR14L→partner) and Y-score (partner→PRR14L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CCNB1 →	+1.245	+0.563	<.001	<.001	3	5
LSCC	UFD1 →	+0.469	+0.368	<.001	<.001	3	5
OV	KIF20A →	+1.157	+1.157	.002	.002	3	4
OV	CDCA2 →	+1.124	+0.805	.006	.001	3	4
LSCC	THOC3 →	+0.623	+0.287	<.001	<.001	3	4
BRCA	NEK2 →	+0.717	+0.351	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,731 associations by consensus.

Exploration

PRR14L survival (RNA) · tumor vs normal (RNA) · all PRR14L data types