PRR14L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRR14L mutation is significantly associated with the RNA expression of many other genes, with 2,737 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR14L-associated genes across cancer lineages are LINC02745, RNA5SP34, and VTI1BP3. Each is linked with PRR14L in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR14L-to-partner and partner-to-PRR14L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR14L→partner) and Y-score (partner→PRR14L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCLINC02745 →+0.044+4.758<.001.00632
BRCARNA5SP34 →+0.175+7.471.009.00832
BRCAVTI1BP3 →+0.120+5.378<.001.00632
BRCAMIR4462 →+0.544+5.045.001.00932
UCECDUSP15 →-0.548-1.563.001<.00132
UCECTHRB →-0.637-2.512<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,737 associations by consensus.

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