Across TCGA patient cohorts, PRR14L mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR14L-associated genes across cancer lineages are EGFR_pY1068, PCNA, and Caspase-7-cleavedD198. Each is linked with PRR14L in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR14L-to-partner and partner-to-PRR14L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR14L→partner) and Y-score (partner→PRR14L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.248	-1.874	<.001	.002	3	2
COAD	PCNA →	+0.280	+2.178	.016	.035	3	2
COAD	Caspase-7-cleavedD198 →	+1.430	+3.330	<.001	.005	3	2
UCEC	4E-BP1 →	+0.226	+1.795	.004	.007	3	2
COAD	Lck →	+0.306	+2.195	.033	.034	3	2
COAD	PREX1 →	+0.200	+2.820	.041	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration

PRR14L survival (RNA) · tumor vs normal (RNA) · all PRR14L data types