Across TCGA cell cohorts, PRR14L mutation is significantly associated with the RNA expression of many other genes, with 1,724 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PRR14L-associated genes across cancer lineages are CLEC9A, OR4K1, and RLN3. Each is linked with PRR14L in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR14L-to-partner and partner-to-PRR14L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR14L→partner) and Y-score (partner→PRR14L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CLEC9A →	+0.013	+3.273	<.001	.004	3	2
SOFT_TISSUE	OR4K1 →	+0.015	+4.977	<.001	.002	3	2
SOFT_TISSUE	RLN3 →	+0.030	+4.369	<.001	.008	3	2
SOFT_TISSUE	TARM1 →	+0.039	+4.369	<.001	.008	3	2
URINARY_TRACT	PRAMEF4 →	+0.017	+5.044	<.001	<.001	3	2
BREAST	MYH8 →	+0.015	+3.781	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,724 associations by consensus.

Exploration

PRR14L survival (RNA) · tumor vs normal (RNA) · all PRR14L data types