PRR11

Across TCGA patient cohorts, PRR11 protein abundance is significantly associated with the RNA expression of many other genes, with 20,455 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRR11-associated genes across cancer lineages are CACTIN, APBA3, and KRT8P50. Each is linked with PRR11 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR11-to-partner and partner-to-PRR11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRR11 versus CACTIN in HNSC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR11→partner) and Y-score (partner→PRR11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CACTIN →	+0.667	+0.406	<.001	.002	3	2
BRCA	APBA3 →	+0.748	+0.927	.008	.002	3	2
LSCC	KRT8P50 →	+0.135	+0.588	.002	<.001	3	2
BRCA	EIF3I →	+0.530	+0.944	.006	.006	3	2
HNSC	TFIP11 →	+0.718	+0.515	.009	.003	3	1
HNSC	SNU13 →	+0.820	+0.639	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,455 associations by consensus.

PRR11 vs CACTIN — HNSC

Explore this scatter interactively →