PRR11

Across TCGA pan-cancer cohorts, PRR11 RNA is linked to patient survival in 32 of 34 cancer types, making it the most broadly survival-associated PRR11 data layer compared with 6 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher PRR11 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PRR11 expression acts as an unfavorable survival marker, although some lineages such as THYM and OV show a favorable association.

KIRP, ACC, and MESO are the cancer types where PRR11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.564	0.789	<.001	171	view →
ACC	DFS	Median	All	0.240	0.641	<.001	145	view →
MESO	OS	Median	All	0.355	0.723	<.001	132	view →
KICH	DFS	Median	III,IV	0.223	0.943	<.001	95	view →
LIHC	DFS	Median	All	0.450	0.633	<.001	89	view →
BLCA	DFS	Tertile	All	0.522	0.693	<.001	84	view →
LUAD	OS	Tertile	All	0.578	0.777	<.001	63	view →
PAAD	OS	Quartile	All	0.288	0.659	<.001	55	view →
LGG	OS	Median	All	0.729	0.901	<.001	49	view →
CESC	DFS	Median	III,IV	0.221	0.684	.013	40	view →
KIRC	DFS	Tertile	All	0.731	0.854	.010	36	view →
UCEC	DFS	Quartile	All	0.622	0.869	<.001	34	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 32 lineages.

PRR11–KIRP (OS)

Open the KIRP breakdown →