PRPSAP2

Across TCGA patient cohorts, PRPSAP2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,954 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPSAP2-associated genes across cancer lineages are MED9, TRIM16L, and DRG2. Each is linked with PRPSAP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRPSAP2-to-partner and partner-to-PRPSAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRPSAP2 versus MED9 in LSCC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPSAP2→partner) and Y-score (partner→PRPSAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MED9 →	+0.558	+0.334	<.001	<.001	3	7
LSCC	TRIM16L →	+1.445	+0.215	<.001	<.001	3	5
BRCA	DRG2 →	+0.561	+0.250	<.001	<.001	3	5
HNSC	TTC19 →	+0.620	+0.267	.005	<.001	3	5
LSCC	GID4 →	+0.604	+0.287	<.001	<.001	3	5
LSCC	RAVER2 →	+0.813	+0.322	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,954 associations by consensus.

PRPSAP2 vs MED9 — LSCC

Explore this scatter interactively →