PRPSAP2

Across TCGA cell cohorts, PRPSAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,959 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRPSAP2-associated GO terms across cancer lineages are 5-phosphoribose 1-diphosphate metabolic process, 5-phosphoribose 1-diphosphate biosynthetic process, and Mitotic spindle assembly. Each is linked with PRPSAP2 in more than 17 cancer types. Because this analysis shows association rather than direction, both PRPSAP2-to-partner and partner-to-PRPSAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 5-phosphoribose 1-diphosphate metabolic process grouped by PRPSAP2-low versus PRPSAP2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPSAP2→partner) and Y-score (partner→PRPSAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	5-phosphoribose 1-diphosphate metabolic process →	+0.180	+1.013	<.001	<.001	3	18
BREAST	5-phosphoribose 1-diphosphate biosynthetic process →	+0.180	+1.013	<.001	<.001	3	18
URINARY_TRACT	Mitotic spindle assembly →	+0.080	+0.582	<.001	<.001	3	14
OVARY	Purine nucleobase biosynthetic process →	+0.126	+0.955	.001	<.001	3	13
LUNG_SCLC	Regulation of RNA export from nucleus →	+0.106	+0.784	<.001	<.001	3	13
OVARY	7-methylguanosine mRNA capping →	+0.089	+0.651	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,959 associations by consensus.

5-phosphoribose 1-diphosphate metabolic process by PRPSAP2 expression — BREAST

Explore this box plot interactively →