PRPSAP1

Across TCGA pan-cancer cohorts, PRPSAP1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PRPSAP1 data layer compared with 20 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PRPSAP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PRPSAP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

UCEC, PDAC, and LUAD are the cancer types where PRPSAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	II,III,IV	1.000	0.453	.018	12	view →
PDAC	OS	Median	All	0.791	0.932	.019	9	view →
LUAD	DFS	Quartile	All	1.000	0.586	.030	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PRPSAP1–UCEC (DFS)

Open the UCEC breakdown →