PRPSAP1

Across TCGA patient cohorts, PRPSAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,539 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPSAP1-associated genes across cancer lineages are PRPS2, NUP85, and KPNA2. Each is linked with PRPSAP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRPSAP1-to-partner and partner-to-PRPSAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRPSAP1 versus PRPS2 in HNSC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPSAP1→partner) and Y-score (partner→PRPSAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PRPS2 →	+1.201	+0.299	<.001	<.001	3	7
BRCA	NUP85 →	+0.601	+0.360	<.001	<.001	3	7
HNSC	KPNA2 →	+0.798	+0.240	.002	<.001	3	7
UCEC	BIRC5 →	+1.176	+0.212	.001	<.001	3	7
UCEC	MRPS7 →	+0.821	+0.197	.001	.001	3	6
LSCC	SAP30BP →	+0.377	+0.251	.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,539 associations by consensus.

PRPSAP1 vs PRPS2 — HNSC

Explore this scatter interactively →