PRPSAP1

Across TCGA cell cohorts, PRPSAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,605 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRPSAP1-associated GO terms across cancer lineages are Negative regulation of beige fat cell differentiation, Microtubule cytoskeleton organization involved in mitosis, and Positive regulation of mitotic cytokinesis. Each is linked with PRPSAP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both PRPSAP1-to-partner and partner-to-PRPSAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of beige fat cell differentiation grouped by PRPSAP1-low versus PRPSAP1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPSAP1→partner) and Y-score (partner→PRPSAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of beige fat cell differentiation →	+0.162	+0.582	.002	.002	3	12
BLOOD_Myeloma	Microtubule cytoskeleton organization involved in mitosis →	+0.101	+0.946	<.001	.003	3	12
BREAST	Positive regulation of mitotic cytokinesis →	+0.158	+0.842	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Mitotic cytokinesis →	+0.089	+0.745	.001	.006	2	12
BLOOD_Myeloma	Regulation of centrosome cycle →	+0.072	+0.657	<.001	.004	3	11
URINARY_TRACT	Negative regulation of cell cycle process →	+0.061	+0.710	.001	.004	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,605 associations by consensus.

Negative regulation of beige fat cell differentiation by PRPSAP1 expression — LIVER

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