PRPH

Across TCGA patient cohorts, PRPH RNA expression is significantly associated with the protein abundance of many other proteins, with 8,428 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPH-associated proteins across cancer lineages are TAGLN_S181, TPPP, and CILP. Each is linked with PRPH in more than 2 cancer types. Because this analysis shows association rather than direction, both PRPH-to-partner and partner-to-PRPH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRPH versus TAGLN_S181 in COAD, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPH→partner) and Y-score (partner→PRPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TAGLN_S181 →	+0.556	+0.277	<.001	<.001	3	3
COAD	TPPP →	+0.465	+0.275	<.001	<.001	3	3
UCEC	CILP →	+0.748	+0.477	.002	.001	3	3
COAD	CKB →	+0.759	+0.265	<.001	<.001	3	3
LSCC	MAP1LC3A →	+0.587	+0.257	.001	<.001	3	3
LSCC	XPO1 →	+0.258	+0.240	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,428 associations by consensus.

PRPH vs TAGLN_S181 — COAD

Explore this scatter interactively →