PRPH

Across TCGA patient cohorts, PRPH protein abundance is significantly associated with the RNA expression of many other genes, with 15,395 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PRPH-associated genes across cancer lineages are C1QTNF2, LMOD1, and PI16. Each is linked with PRPH in more than 6 cancer types. Because this analysis shows association rather than direction, both PRPH-to-partner and partner-to-PRPH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRPH versus C1QTNF2 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPH→partner) and Y-score (partner→PRPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	C1QTNF2 →	+0.853	+0.778	<.001	<.001	3	7
COAD	LMOD1 →	+1.273	+0.712	<.001	<.001	3	7
HNSC	PI16 →	+1.679	+0.578	<.001	<.001	3	7
OV	SRPX →	+1.204	+0.666	<.001	<.001	3	6
COAD	OGN →	+1.682	+0.630	<.001	<.001	3	6
HNSC	SGCA →	+1.520	+0.765	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,395 associations by consensus.

PRPH vs C1QTNF2 — BRCA

Explore this scatter interactively →