PRPH

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRPH mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. CESC shows the largest number of these associations.

The most reproducible PRPH-associated genes across cancer lineages are naive B-cells. Each is linked with PRPH in more than 1 cancer types. Because this analysis shows association rather than direction, both PRPH-to-partner and partner-to-PRPH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, naive B-cells grouped by PRPH-low versus PRPH-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPH→partner) and Y-score (partner→PRPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCnaive B-cells →+0.009+2.922.006.04631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

naive B-cells by PRPH expression — CESC

Box plot of naive B-cells in PRPH-low vs PRPH-high samples in CESC.

Explore this box plot interactively →

Exploration