PRPF40B

Across TCGA patient cohorts, PRPF40B protein abundance is significantly associated with the RNA expression of many other genes, with 13,214 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPF40B-associated genes across cancer lineages are ZC2HC1C, EIF2B2, and RMND5A. Each is linked with PRPF40B in more than 3 cancer types. Because this analysis shows association rather than direction, both PRPF40B-to-partner and partner-to-PRPF40B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRPF40B versus ZC2HC1C in LSCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF40B→partner) and Y-score (partner→PRPF40B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZC2HC1C →	+0.340	+0.423	.001	<.001	3	4
LUAD	EIF2B2 →	+0.491	+0.337	<.001	.001	3	4
HNSC	RMND5A →	+0.475	+0.274	.001	<.001	3	4
LSCC	DNAAF2 →	+0.464	+0.441	<.001	<.001	3	4
HNSC	GLRX5 →	+0.551	+0.263	.002	.003	3	4
HNSC	BCDIN3D →	+0.480	+0.374	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,214 associations by consensus.

PRPF40B vs ZC2HC1C — LSCC

Explore this scatter interactively →