Across TCGA patient cohorts, PRPF39 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,063 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPF39-associated proteins across cancer lineages are FKBP3, MTA1, and SUPT16H. Each is linked with PRPF39 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRPF39-to-partner and partner-to-PRPF39 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF39→partner) and Y-score (partner→PRPF39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FKBP3 →	+0.386	+0.528	<.001	<.001	3	8
GBM	MTA1 →	+0.443	+0.465	<.001	<.001	3	7
GBM	SUPT16H →	+0.368	+0.470	<.001	<.001	3	7
GBM	PPP4R3A →	+0.287	+0.465	<.001	<.001	3	6
GBM	PAPOLA →	+0.298	+0.564	<.001	<.001	3	6
LSCC	BAG5 →	+0.326	+0.445	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,063 associations by consensus.

Exploration

PRPF39 survival (RNA) · tumor vs normal (RNA) · all PRPF39 data types