Across TCGA patient cohorts, PRPF39 mutation is significantly associated with the RNA expression of many other genes, with 2,433 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRPF39-associated genes across cancer lineages are MIR4478, RN7SL248P, and RNU6-99P. Each is linked with PRPF39 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRPF39-to-partner and partner-to-PRPF39 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF39→partner) and Y-score (partner→PRPF39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	MIR4478 →	+0.653	+5.770	<.001	.003	3	2
UCEC	RN7SL248P →	+0.045	+2.722	<.001	.002	3	2
LGG	RNU6-99P →	+0.248	+7.977	<.001	.007	3	2
HNSC	MIR3169 →	+0.347	+7.954	<.001	.008	3	2
HNSC	RN7SL185P →	+0.134	+7.954	<.001	.008	3	2
CESC	OR1E3 →	+0.038	+5.306	.007	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,433 associations by consensus.

Exploration

PRPF39 survival (RNA) · tumor vs normal (RNA) · all PRPF39 data types