PRPF38B

Across TCGA cell cohorts, PRPF38B mutation is significantly associated with the mutation status of many other genes, with 1,719 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PRPF38B-associated genes across cancer lineages are VWA3B, ZBTB41, and ADCY1. Each is linked with PRPF38B in more than 3 cancer types. Because this analysis shows association rather than direction, both PRPF38B-to-partner and partner-to-PRPF38B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VWA3B grouped by PRPF38B-low versus PRPF38B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF38B→partner) and Y-score (partner→PRPF38B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	VWA3B →	+4.584	+4.584	.007	.007	1	4
BLOOD_Lymphoma	ZBTB41 →	+5.584	+5.014	.003	.003	1	4
LARGE_INTESTINE	ADCY1 →	+2.099	+4.064	.001	.001	1	4
STOMACH	PKDREJ →	+4.807	+4.807	.008	.008	1	3
BLOOD_Lymphoma	CEP350 →	+3.169	+4.601	.003	.003	1	3
STOMACH	MMP16 →	+4.807	+4.807	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,719 associations by consensus.

VWA3B by PRPF38B expression — BLOOD_Lymphoma

Explore this box plot interactively →