PRPF38AP2

Across TCGA patient cohorts, PRPF38AP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,458 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRPF38AP2-associated GO terms across cancer lineages are RNA 3'-end processing, Protein autoubiquitination, and Smoothened signaling pathway. Each is linked with PRPF38AP2 in more than 17 cancer types. Because this analysis shows association rather than direction, both PRPF38AP2-to-partner and partner-to-PRPF38AP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA 3'-end processing grouped by PRPF38AP2-low versus PRPF38AP2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF38AP2→partner) and Y-score (partner→PRPF38AP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA 3'-end processing →	+0.051	+0.166	<.001	<.001	3	18
STAD	Protein autoubiquitination →	+0.045	+0.135	<.001	<.001	3	16
ESCA	Smoothened signaling pathway →	+0.057	+0.184	<.001	<.001	3	16
STAD	Telomere maintenance via telomere lengthening →	+0.047	+0.149	<.001	<.001	3	16
STAD	Regulation of telomere maintenance →	+0.047	+0.140	<.001	<.001	3	16
ESCA	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.078	+0.210	.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,458 associations by consensus.

RNA 3'-end processing by PRPF38AP2 expression — STAD

Explore this box plot interactively →