PROX1

Across TCGA patient cohorts, PROX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,635 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PROX1-associated proteins across cancer lineages are PROX1_S511, PROX1_S179, and PROX1_S199. Each is linked with PROX1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PROX1-to-partner and partner-to-PROX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PROX1 versus PROX1_S511 in BRCA, with a Pearson correlation of 0.78.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PROX1→partner) and Y-score (partner→PROX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PROX1_S511 →	+1.037	+1.140	<.001	<.001	3	8
LUAD	PROX1_S179 →	+0.993	+1.141	<.001	<.001	3	7
LSCC	PROX1_S199 →	+1.296	+1.125	<.001	<.001	3	7
GBM	RBM47 →	-0.334	-0.559	.002	.001	3	5
LUAD	HSPB1 →	-0.526	-1.483	<.001	<.001	3	5
GBM	PSIP1_S106 →	+0.456	+0.872	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,635 associations by consensus.

PROX1 vs PROX1_S511 — BRCA

Explore this scatter interactively →