PROX1

Across TCGA patient cohorts, PROX1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,594 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PROX1-associated genes across cancer lineages are CEMIP, TRIM24, and BCL2L15. Each is linked with PROX1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PROX1-to-partner and partner-to-PROX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PROX1 versus CEMIP in LUAD, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PROX1→partner) and Y-score (partner→PROX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CEMIP →	+2.437	+1.339	.003	.003	3	3
CCRCC	TRIM24 →	+0.692	+1.194	<.001	.003	3	3
UCEC	BCL2L15 →	+1.074	+1.216	<.001	<.001	3	3
PDAC	LINC00342 →	+0.990	+0.536	.008	.008	3	3
LSCC	ABCA11P →	+0.813	+1.638	.005	.001	3	3
UCEC	SNHG22 →	+0.557	+1.678	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,594 associations by consensus.

PROX1 vs CEMIP — LUAD

Explore this scatter interactively →