PROSER1

Across TCGA cell cohorts, PROSER1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,627 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PROSER1-associated GO terms across cancer lineages are Regulation of mRNA catabolic process, Positive regulation of cytoplasmic mRNA processing body assembly, and Ribosomal protein import into nucleus. Each is linked with PROSER1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PROSER1-to-partner and partner-to-PROSER1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA catabolic process grouped by PROSER1-low versus PROSER1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PROSER1→partner) and Y-score (partner→PROSER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mRNA catabolic process →	+0.081	+1.223	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.152	+1.112	<.001	<.001	3	14
STOMACH	Ribosomal protein import into nucleus →	+0.100	+0.777	.003	.005	2	15
LUNG_NSCLC_LUSC	Extracellular matrix organization →	-0.190	-1.029	<.001	<.001	3	13
SOFT_TISSUE	Regulation of mRNA stability →	+0.066	+0.908	<.001	<.001	3	13
LUNG_NSCLC_LUSC	External encapsulating structure organization →	-0.191	-1.029	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,627 associations by consensus.

Regulation of mRNA catabolic process by PROSER1 expression — SOFT_TISSUE

Explore this box plot interactively →