PRORP

Across TCGA patient cohorts, PRORP RNA expression is significantly associated with the protein abundance of many other proteins, with 12,992 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRORP-associated proteins across cancer lineages are PPP4R3A, STRN3, and SNX5. Each is linked with PRORP in more than 5 cancer types. Because this analysis shows association rather than direction, both PRORP-to-partner and partner-to-PRORP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRORP versus PPP4R3A in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRORP→partner) and Y-score (partner→PRORP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP4R3A →	+0.377	+0.510	<.001	<.001	3	6
LUAD	STRN3 →	+0.214	+0.465	<.001	<.001	3	6
UCEC	SNX5 →	-0.306	-0.551	<.001	<.001	3	5
GBM	MTA1 →	+0.357	+0.323	<.001	<.001	3	5
GBM	SNRPD2 →	+0.225	+0.405	.007	.002	3	4
GBM	SUPT16H →	+0.507	+0.465	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,992 associations by consensus.

PRORP vs PPP4R3A — GBM

Explore this scatter interactively →