PROM2

Across TCGA cell cohorts, PROM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,643 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible PROM2-associated GO terms across cancer lineages are Desmosome assembly, Negative regulation of actin filament bundle assembly, and Establishment or maintenance of apical/basal cell polarity. Each is linked with PROM2 in more than 11 cancer types. Because this analysis shows association rather than direction, both PROM2-to-partner and partner-to-PROM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Desmosome assembly grouped by PROM2-low versus PROM2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PROM2→partner) and Y-score (partner→PROM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Desmosome assembly →	+0.413	+3.520	<.001	<.001	3	11
OESOPHAGUS	Negative regulation of actin filament bundle assembly →	+0.158	+3.407	.001	.003	2	12
OESOPHAGUS	Establishment or maintenance of apical/basal cell polarity →	+0.169	+3.811	.001	.001	3	11
OESOPHAGUS	Cell-cell adhesion mediated by cadherin →	+0.253	+3.222	<.001	.009	2	12
OESOPHAGUS	Establishment or maintenance of bipolar cell polarity →	+0.169	+3.811	.001	.001	3	11
URINARY_TRACT	Response to indole-3-methanol →	+0.205	+3.624	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,643 associations by consensus.

Desmosome assembly by PROM2 expression — STOMACH

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