PROM1

Across TCGA patient cohorts, PROM1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,738 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PROM1-associated genes across cancer lineages are TRIM29, CA8, and CD200R1. Each is linked with PROM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PROM1-to-partner and partner-to-PROM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PROM1 versus TRIM29 in BRCA, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PROM1→partner) and Y-score (partner→PROM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TRIM29 →	+2.053	+0.970	<.001	<.001	3	3
UCEC	CA8 →	+0.962	+0.793	.005	.001	3	3
LSCC	CD200R1 →	-0.809	-0.899	.003	.002	2	4
OV	BATF2 →	-1.090	-1.036	<.001	.001	3	3
BRCA	SLC5A1 →	+1.188	+0.636	<.001	<.001	3	3
CCRCC	LINC01559 →	+1.577	+0.548	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,738 associations by consensus.

PROM1 vs TRIM29 — BRCA

Explore this scatter interactively →