PROM1

Across TCGA cell cohorts, PROM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,913 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PROM1-associated GO terms across cancer lineages are Positive regulation of bone development, Protein transport within lipid bilayer, and Keratinocyte development. Each is linked with PROM1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PROM1-to-partner and partner-to-PROM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of bone development grouped by PROM1-low versus PROM1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PROM1→partner) and Y-score (partner→PROM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of bone development →	+1.026	+4.144	<.001	<.001	3	7
PANCREAS	Protein transport within lipid bilayer →	+0.311	+2.313	<.001	.001	3	6
CNS	Keratinocyte development →	-0.335	-1.117	.006	.003	3	6
LUNG_SCLC	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.034	-2.582	<.001	<.001	3	6
LIVER	Regulation of bone development →	+0.214	+4.500	.001	<.001	3	6
SKIN	Actin filament-based transport →	+0.096	+0.702	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,913 associations by consensus.

Positive regulation of bone development by PROM1 expression — LUNG_SCLC

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