PRODH

Across TCGA patient cohorts, PRODH RNA expression is significantly associated with the protein abundance of many other proteins, with 12,994 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRODH-associated proteins across cancer lineages are PPP1R18, KIF21A_S1212, and MANF. Each is linked with PRODH in more than 3 cancer types. Because this analysis shows association rather than direction, both PRODH-to-partner and partner-to-PRODH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRODH versus PPP1R18 in LSCC, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRODH→partner) and Y-score (partner→PRODH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPP1R18 →	-0.330	-0.918	<.001	.001	3	4
LSCC	KIF21A_S1212 →	+0.698	+0.706	<.001	.004	3	4
LSCC	MANF →	-0.509	-0.960	<.001	.001	3	4
LUAD	SPATS2 →	-0.243	-1.205	.003	<.001	3	4
LUAD	SPCS3 →	-0.492	-1.155	.001	.002	3	4
CCRCC	CEBPB →	-0.455	-0.881	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,994 associations by consensus.

PRODH vs PPP1R18 — LSCC

Explore this scatter interactively →