PRODH

Across TCGA cell cohorts, PRODH RNA expression is significantly associated with the go_rna of many other GO terms, with 4,081 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PRODH-associated GO terms across cancer lineages are Establishment of epithelial cell apical/basal polarity, Centromeric sister chromatid cohesion, and Peptidyl-lysine oxidation. Each is linked with PRODH in more than 11 cancer types. Because this analysis shows association rather than direction, both PRODH-to-partner and partner-to-PRODH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of epithelial cell apical/basal polarity grouped by PRODH-low versus PRODH-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRODH→partner) and Y-score (partner→PRODH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Establishment of epithelial cell apical/basal polarity →	-0.168	-3.599	<.001	<.001	3	12
OESOPHAGUS	Centromeric sister chromatid cohesion →	-0.129	-1.803	.001	.004	3	11
BONE	Peptidyl-lysine oxidation →	-1.269	-0.921	<.001	.006	3	9
BONE	Copper ion export →	-0.138	-0.943	.001	.001	3	9
BONE	Muscle organ development →	-0.103	-0.804	<.001	.003	2	10
LIVER	Negative regulation of lymphoid progenitor cell differentiation →	+0.241	+2.722	.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,081 associations by consensus.

Establishment of epithelial cell apical/basal polarity by PRODH expression — BREAST

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