PROCR

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PROCR protein abundance is significantly associated with the RNA expression of many other genes, with 16,595 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PROCR-associated genes across cancer lineages are STAB1, LILRB5, and TGFBI. Each is linked with PROCR in more than 5 cancer types. Because this analysis shows association rather than direction, both PROCR-to-partner and partner-to-PROCR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PROCR versus STAB1 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PROCR→partner) and Y-score (partner→PROCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVSTAB1 →+0.975+0.501<.001<.00136
GBMLILRB5 →+0.612+0.484<.001.00236
CCRCCTGFBI →+1.470+0.340<.001<.00136
BRCAF13A1 →+1.814+0.730<.001<.00136
GBMSLC9A9 →+0.734+0.618<.001<.00136
OVTMEM255B →+0.521+0.535<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,595 associations by consensus.

PROCR vs STAB1 — OV

Per-sample scatter of PROCR vs STAB1 in OV (Pearson r = 0.41).

Explore this scatter interactively →

Exploration