PROCR

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PROCR mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PROCR-associated genes across cancer lineages are GMP and CLP. Each is linked with PROCR in more than 1 cancer types. Because this analysis shows association rather than direction, both PROCR-to-partner and partner-to-PROCR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by PROCR-low versus PROCR-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PROCR→partner) and Y-score (partner→PROCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMGMP →+0.060+3.221<.001.01032
UCECCLP →-0.100-2.957.005.03711
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GMP by PROCR expression — SKCM

Box plot of GMP in PROCR-low vs PROCR-high samples in SKCM.

Explore this box plot interactively →

Exploration