PROC

Across TCGA patient cohorts, PROC RNA expression is significantly associated with the protein abundance of many other proteins, with 7,606 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PROC-associated proteins across cancer lineages are SSC5D, SH3BGRL2, and CAMP. Each is linked with PROC in more than 3 cancer types. Because this analysis shows association rather than direction, both PROC-to-partner and partner-to-PROC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PROC versus SSC5D in BRCA, with a Pearson correlation of 0.22.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PROC→partner) and Y-score (partner→PROC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SSC5D →	+0.564	+0.354	.003	.009	3	4
LUAD	SH3BGRL2 →	+0.442	+0.888	.002	.001	3	4
GBM	CAMP →	-1.584	-0.409	<.001	.001	3	3
LUAD	EPB41L5 →	+0.307	+0.838	<.001	<.001	3	3
LUAD	CDC42BPA →	+0.419	+0.512	.001	.006	3	3
GBM	BMP1 →	-0.442	-0.303	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,606 associations by consensus.

PROC vs SSC5D — BRCA

Explore this scatter interactively →