PRNT

Across TCGA patient cohorts, PRNT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,255 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRNT-associated GO terms across cancer lineages are Negative regulation of binding, Protein polymerization, and Regulation of actin filament organization. Each is linked with PRNT in more than 8 cancer types. Because this analysis shows association rather than direction, both PRNT-to-partner and partner-to-PRNT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of binding grouped by PRNT-low versus PRNT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRNT→partner) and Y-score (partner→PRNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of binding →	+0.051	+0.138	<.001	<.001	3	9
ESCA	Protein polymerization →	+0.071	+0.160	<.001	.001	3	9
ESCA	Regulation of actin filament organization →	+0.069	+0.140	<.001	.006	3	8
STAD	Nucleoside phosphate biosynthetic process →	+0.053	+0.130	<.001	<.001	3	8
STAD	Organic acid transmembrane transport →	+0.029	+0.127	<.001	<.001	3	8
STAD	Regulation of cell division →	+0.042	+0.115	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,255 associations by consensus.

Negative regulation of binding by PRNT expression — STAD

Explore this box plot interactively →