PRNT

Across TCGA pan-cancer cohorts, PRNT RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of PRNT’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where PRNT RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PRNT is over-expressed in tumor.

ESCA are the cancer types where PRNT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PRNT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	+0.025	.037	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

PRNT–ESCA

Open the ESCA breakdown →