PRMT8

Across TCGA patient cohorts, PRMT8 protein abundance is significantly associated with the RNA expression of many other genes, with 3,708 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRMT8-associated genes across cancer lineages are ARF6, RNU6-1310P, and RIMS1. Each is linked with PRMT8 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRMT8-to-partner and partner-to-PRMT8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRMT8 versus ARF6 in PDAC, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT8→partner) and Y-score (partner→PRMT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ARF6 →	-0.422	-0.525	.004	.006	3	2
PDAC	RNU6-1310P →	-0.875	-0.525	.002	.007	3	2
GBM	RIMS1 →	+1.163	+0.550	<.001	<.001	3	2
PDAC	HPS4 →	-0.450	-0.548	.001	.003	3	1
PDAC	DEPDC5 →	-0.227	-0.542	.003	.002	3	1
PDAC	CBX7 →	-0.394	-0.480	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,708 associations by consensus.

PRMT8 vs ARF6 — PDAC

Explore this scatter interactively →