PRMT5P1

Across TCGA patient cohorts, PRMT5P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,196 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRMT5P1-associated GO terms across cancer lineages are Mitochondrial translation, Mitochondrial gene expression, and Ribosomal large subunit biogenesis. Each is linked with PRMT5P1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PRMT5P1-to-partner and partner-to-PRMT5P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by PRMT5P1-low versus PRMT5P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT5P1→partner) and Y-score (partner→PRMT5P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial translation →	+0.055	+0.119	<.001	<.001	3	15
STAD	Mitochondrial gene expression →	+0.051	+0.128	<.001	<.001	3	14
ESCA	Ribosomal large subunit biogenesis →	+0.059	+0.160	.003	.002	3	14
ESCA	Telomerase RNA localization →	+0.059	+0.227	.002	<.001	3	12
STAD	Nucleoside phosphate biosynthetic process →	+0.039	+0.094	<.001	<.001	3	12
ESCA	Regulation of organelle assembly →	+0.054	+0.177	.002	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,196 associations by consensus.

Mitochondrial translation by PRMT5P1 expression — STAD

Explore this box plot interactively →