PRLHR

Across TCGA patient cohorts, PRLHR RNA expression is significantly associated with the go_rna of many other GO terms, with 6,613 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible PRLHR-associated GO terms across cancer lineages are Axon extension, Positive regulation of peptide secretion, and Regulation of neuron differentiation. Each is linked with PRLHR in more than 9 cancer types. Because this analysis shows association rather than direction, both PRLHR-to-partner and partner-to-PRLHR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Axon extension grouped by PRLHR-low versus PRLHR-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRLHR→partner) and Y-score (partner→PRLHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Axon extension →	+0.070	+0.235	<.001	.001	3	10
PAAD	Positive regulation of peptide secretion →	+0.037	+0.235	<.001	<.001	3	9
STAD	Regulation of neuron differentiation →	+0.026	+0.153	<.001	.001	3	9
STAD	Regulation of axonogenesis →	+0.053	+0.252	<.001	<.001	3	8
STAD	Establishment of protein localization to chromosome →	+0.051	+0.131	<.001	.006	2	9
ESCA	Regulation of double-strand break repair via homologous recombination →	+0.056	+0.080	<.001	.004	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,613 associations by consensus.

Axon extension by PRLHR expression — STAD

Explore this box plot interactively →