PRLHR

Across TCGA patient cohorts, PRLHR mutation is significantly associated with the RNA expression of many other genes, with 1,222 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRLHR-associated genes across cancer lineages are RNA5SP198, PKN3, and INS. Each is linked with PRLHR in more than 3 cancer types. Because this analysis shows association rather than direction, both PRLHR-to-partner and partner-to-PRLHR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP198 grouped by PRLHR-low versus PRLHR-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRLHR→partner) and Y-score (partner→PRLHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP198 →	+0.155	+4.000	<.001	.009	3	4
UCEC	PKN3 →	+0.734	+2.098	<.001	.003	3	3
SKCM	INS →	+0.312	+3.224	<.001	.007	3	3
ESCA	MIR7160 →	+0.627	+4.681	<.001	.006	3	3
UCEC	ITGB1BP1 →	+0.348	+2.606	.006	<.001	3	3
UCEC	CEP89 →	+0.370	+3.332	.009	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,222 associations by consensus.

RNA5SP198 by PRLHR expression — LUAD

Explore this box plot interactively →