PRLHR

Across TCGA cell cohorts, PRLHR RNA expression is significantly associated with the mutation status of many other genes, with 91 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRLHR-associated genes across cancer lineages are DENND4B, URB1, and TRIM66. Each is linked with PRLHR in more than 1 cancer types. Because this analysis shows association rather than direction, both PRLHR-to-partner and partner-to-PRLHR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DENND4B grouped by PRLHR-low versus PRLHR-high in OVARY.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRLHR→partner) and Y-score (partner→PRLHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	DENND4B →	+3.444	+0.018	.003	<.001	3	2
BLOOD_Leukemia	URB1 →	+2.201	+0.004	.006	.005	3	2
BLOOD_Myeloma	TRIM66 →	+3.906	+0.019	.009	<.001	3	1
KIDNEY	KDM3A →	+5.000	+0.030	.005	<.001	3	1
KIDNEY	PHF3 →	+5.000	+0.030	.005	<.001	3	1
KIDNEY	PCDHB12 →	+5.000	+0.030	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 91 associations by consensus.

DENND4B by PRLHR expression — OVARY

Explore this box plot interactively →