PRKY

Across TCGA patient cohorts, PRKY mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PRKY-associated genes across cancer lineages are Mesangial cells. Each is linked with PRKY in more than 1 cancer types. Because this analysis shows association rather than direction, both PRKY-to-partner and partner-to-PRKY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by PRKY-low versus PRKY-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKY→partner) and Y-score (partner→PRKY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Mesangial cells →	+0.013	+4.290	.009	.023	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Mesangial cells by PRKY expression — SKCM

Explore this box plot interactively →