PRKXP1

Across TCGA patient cohorts, PRKXP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,135 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible PRKXP1-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, Positive regulation of post-translational protein modification, and Protein depolymerization. Each is linked with PRKXP1 in more than 30 cancer types. Because this analysis shows association rather than direction, both PRKXP1-to-partner and partner-to-PRKXP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway grouped by PRKXP1-low versus PRKXP1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKXP1→partner) and Y-score (partner→PRKXP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.096	+1.389	<.001	<.001	3	31
DLBC	Positive regulation of post-translational protein modification →	+0.050	+1.295	<.001	<.001	3	31
DLBC	Protein depolymerization →	+0.049	+1.329	<.001	<.001	3	31
DLBC	Centrosome duplication →	+0.069	+1.254	<.001	<.001	3	31
DLBC	Vesicle localization →	+0.043	+1.244	<.001	<.001	3	31
THYM	Protein localization to lysosome →	+0.058	+0.842	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,135 associations by consensus.

Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway by PRKXP1 expression — DLBC

Explore this box plot interactively →