PRKRIP1

Across TCGA patient cohorts, PRKRIP1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,066 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRKRIP1-associated genes across cancer lineages are CPSF4, ALKBH4, and ZKSCAN5. Each is linked with PRKRIP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRKRIP1-to-partner and partner-to-PRKRIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKRIP1 versus CPSF4 in HNSC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKRIP1→partner) and Y-score (partner→PRKRIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CPSF4 →	+0.692	+0.298	<.001	<.001	3	7
UCEC	ALKBH4 →	+0.814	+0.214	.001	<.001	3	7
UCEC	ZKSCAN5 →	+0.585	+0.255	<.001	<.001	3	7
LSCC	PMPCB →	+0.626	+0.333	<.001	<.001	3	6
UCEC	ZNHIT1 →	+1.034	+0.276	<.001	<.001	3	6
HNSC	GIGYF1 →	+0.799	+0.353	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,066 associations by consensus.

PRKRIP1 vs CPSF4 — HNSC

Explore this scatter interactively →