PRKG2

Across TCGA patient cohorts, PRKG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,190 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRKG2-associated proteins across cancer lineages are UPP1, INPP5D_S971, and VAV3. Each is linked with PRKG2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRKG2-to-partner and partner-to-PRKG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKG2 versus UPP1 in HNSC, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKG2→partner) and Y-score (partner→PRKG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UPP1 →	-0.856	-0.714	<.001	<.001	3	4
BRCA	INPP5D_S971 →	-0.527	-0.562	.002	.005	3	4
GBM	VAV3 →	-0.407	-0.654	<.001	.001	3	3
HNSC	SP110 →	-0.489	-0.664	<.001	<.001	3	3
HNSC	SP110_S244 →	-0.480	-0.638	<.001	<.001	3	3
LSCC	SP110_S380 →	-0.550	-0.653	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,190 associations by consensus.

PRKG2 vs UPP1 — HNSC

Explore this scatter interactively →