PRKCQ

Across TCGA patient cohorts, PRKCQ RNA expression is significantly associated with the protein abundance of many other proteins, with 18,227 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRKCQ-associated proteins across cancer lineages are PRKCQ_S695, PRKCQ_T538, and PRKCQ_S323. Each is linked with PRKCQ in more than 9 cancer types. Because this analysis shows association rather than direction, both PRKCQ-to-partner and partner-to-PRKCQ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKCQ versus PRKCQ_S695 in GBM, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCQ→partner) and Y-score (partner→PRKCQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRKCQ_S695 →	+1.024	+1.017	<.001	<.001	3	10
UCEC	PRKCQ_T538 →	+1.739	+1.526	<.001	<.001	3	9
OV	PRKCQ_S323 →	+1.295	+0.849	.002	.006	3	8
BRCA	PRKCQ_S685 →	+1.365	+1.091	<.001	<.001	3	8
BRCA	ZAP70 →	+0.817	+1.140	<.001	<.001	3	7
GBM	CYLD →	+0.345	+0.705	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,227 associations by consensus.

PRKCQ vs PRKCQ_S695 — GBM

Explore this scatter interactively →