PRKCQ

Across TCGA patient cohorts, PRKCQ protein abundance is significantly associated with the RNA expression of many other genes, with 11,108 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRKCQ-associated genes across cancer lineages are PRKCQ-AS1, KLRG1, and CD8A. Each is linked with PRKCQ in more than 8 cancer types. Because this analysis shows association rather than direction, both PRKCQ-to-partner and partner-to-PRKCQ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKCQ versus PRKCQ-AS1 in UCEC, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCQ→partner) and Y-score (partner→PRKCQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRKCQ-AS1 →	+1.243	+0.748	<.001	<.001	3	9
UCEC	KLRG1 →	+0.725	+0.569	.001	.004	3	6
BRCA	CD8A →	+1.630	+0.848	<.001	<.001	3	6
HNSC	TRGV10 →	+1.001	+0.478	.001	<.001	3	6
BRCA	TRBC2 →	+1.747	+0.767	<.001	<.001	3	6
HNSC	SLA2 →	+0.862	+0.448	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,108 associations by consensus.

PRKCQ vs PRKCQ-AS1 — UCEC

Explore this scatter interactively →