PRKCE

Across TCGA patient cohorts, PRKCE protein abundance is significantly associated with the RNA expression of many other genes, with 10,746 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRKCE-associated genes across cancer lineages are GPM6A, ABCA3, and RPL26P15. Each is linked with PRKCE in more than 4 cancer types. Because this analysis shows association rather than direction, both PRKCE-to-partner and partner-to-PRKCE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKCE versus GPM6A in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCE→partner) and Y-score (partner→PRKCE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GPM6A →	+0.776	+0.456	<.001	<.001	3	5
LSCC	ABCA3 →	+1.284	+0.205	<.001	.001	3	5
LSCC	RPL26P15 →	+0.821	+0.304	<.001	<.001	3	5
OV	FNDC3B →	-0.673	-0.424	.007	.005	3	4
BRCA	GFRA1 →	+1.467	+0.298	.005	.002	3	4
LSCC	CLEC3B →	+0.708	+0.245	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,746 associations by consensus.

PRKCE vs GPM6A — GBM

Explore this scatter interactively →